Biodesy Delta System measures and differentiates protein conformational changes in real time at high throughput.
Indeed, the 384-well plate format enables thousands of measurements per day.

Services:
- Ligand-induced conformational changes in real-time
- HTS Screening clustering compounds on the basis of their potency, mechanism (allosteric vs orthosteric) and function (agonist vs antagonist)
- Hits identification and validation; Hit-to-Lead and lead optimization step in early drug discovery
- SAR
- Fragment Screening
- Affinity (K_D) from concentration response curves (CRC)
- Kinetics from time course traces

Team:
Dr. Alice Coletti (This email address is being protected from spambots. You need JavaScript enabled to view it.): Lab & Technical Manager of Mass Spectrometry and Biophysical Studies Lab
Prof. Stefano Giovagnoli (This email address is being protected from spambots. You need JavaScript enabled to view it.): Scientific Director of Biophysical Studies Lab